3TWD

glmuC1 in complex with an antibacterial inhibitor

Summary for 3TWD

Entry DOI	10.2210/pdb3twd/pdb
Descriptor	Bifunctional protein glmU, SULFATE ION, 4-({5-[(4-aminophenyl)(phenyl)sulfamoyl]-2,4-dimethoxyphenyl}amino)-4-oxobutanoic acid, ... (4 entities in total)
Functional Keywords	acetyl transferase, uridyl transferase, transferase-transferase inhibitor complex, transferase/transferase inhibitor
Biological source	Escherichia coli
Cellular location	Cytoplasm: P0ACC7
Total number of polymer chains	2
Total formula weight	48190.50
Authors	Lahiri, S.,Otterbein, L. (deposition date: 2011-09-21, release date: 2011-10-19, Last modification date: 2024-02-28)
Primary citation	Buurman, E.T.,Andrews, B.,Gao, N.,Hu, J.,Keating, T.A.,Lahiri, S.,Otterbein, L.R.,Patten, A.D.,Stokes, S.S.,Shapiro, A.B. In Vitro Validation of Acetyltransferase Activity of GlmU as an Antibacterial Target in Haemophilus influenzae. J.Biol.Chem., 286:40734-40742, 2011 Cited by PubMed: 21984832 DOI: 10.1074/jbc.M111.274068 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation