3TT4
Human MMP8 in complex with L-glutamate motif inhibitor
Summary for 3TT4
| Entry DOI | 10.2210/pdb3tt4/pdb |
| Related | 2OY2 3DPE 3TS4 3TSK 3TVC |
| Descriptor | Neutrophil collagenase, ZINC ION, CALCIUM ION, ... (6 entities in total) |
| Functional Keywords | pseudo dipeptides, potent inhibitors, metzincin, zinc metalloprotease, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 1 |
| Total formula weight | 18449.83 |
| Authors | Stura, E.A.,Dive, V.,Devel, L.,Czarny, B.,Beau, F.,Vera, L. (deposition date: 2011-09-14, release date: 2012-06-20, Last modification date: 2023-09-13) |
| Primary citation | Devel, L.,Beau, F.,Amoura, M.,Vera, L.,Cassar-Lajeunesse, E.,Garcia, S.,Czarny, B.,Stura, E.A.,Dive, V. Simple pseudo-dipeptides with a P2' glutamate: a novel inhibitor family of matrix metalloproteases and other metzincins. J.Biol.Chem., 287:26647-26656, 2012 Cited by PubMed: 22689580DOI: 10.1074/jbc.M112.380782 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.88 Å) |
Structure validation
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