3TMH

Crystal structure of dual-specific A-kinase anchoring protein 2 in complex with cAMP-dependent protein kinase A type II alpha and PDZK1

Summary for 3TMH

• Entry DOI: 10.2210/pdb3tmh/pdb
• Descriptor: Na(+)/H(+) exchange regulatory cofactor NHE-RF3, cAMP-dependent protein kinase type II-alpha regulatory subunit, A-kinase anchor protein 10, mitochondrial, ... (4 entities in total)
• Functional Keywords: alpha helical bundle, pdz fold, anchoring protein, pka, pdz proteins, membrane, transport protein-signaling protein complex, transport protein/signaling protein
• Biological source: Homo sapiens (human); More
• Cellular location: Cytoplasm (By similarity): Q5T2W1 P12368; Mitochondrion: O43572
• Total number of polymer chains: 10
• Total formula weight: 65262.08

Authors

Sarma, G.N.,Phan, R.H.,Sankaran, B.,Taylor, S.S. (deposition date: 2011-08-31, release date: 2012-09-05, Last modification date: 2024-02-28)

• Primary citation: Sarma, G.N.,Phan, R.H.,Sankaran, B.,Taylor, S.S.; Differential mode of D-AKAP2 to PKA isoforms: Insights from D-AKAP2 PKA RII PDZK1 ternary complex structure; To be Published,

Experimental method

X-RAY DIFFRACTION (3.8 Å)