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3TMH

Crystal structure of dual-specific A-kinase anchoring protein 2 in complex with cAMP-dependent protein kinase A type II alpha and PDZK1

3TMH の概要
エントリーDOI10.2210/pdb3tmh/pdb
分子名称Na(+)/H(+) exchange regulatory cofactor NHE-RF3, cAMP-dependent protein kinase type II-alpha regulatory subunit, A-kinase anchor protein 10, mitochondrial, ... (4 entities in total)
機能のキーワードalpha helical bundle, pdz fold, anchoring protein, pka, pdz proteins, membrane, transport protein-signaling protein complex, transport protein/signaling protein
由来する生物種Homo sapiens (human)
詳細
細胞内の位置Cytoplasm (By similarity): Q5T2W1 P12368
Mitochondrion: O43572
タンパク質・核酸の鎖数10
化学式量合計65262.08
構造登録者
Sarma, G.N.,Phan, R.H.,Sankaran, B.,Taylor, S.S. (登録日: 2011-08-31, 公開日: 2012-09-05, 最終更新日: 2024-02-28)
主引用文献Sarma, G.N.,Phan, R.H.,Sankaran, B.,Taylor, S.S.
Differential mode of D-AKAP2 to PKA isoforms: Insights from D-AKAP2 PKA RII PDZK1 ternary complex structure
To be Published,
実験手法
X-RAY DIFFRACTION (3.8 Å)
構造検証レポート
Validation report summary of 3tmh
検証レポート(詳細版)ダウンロードをダウンロード

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件を2024-04-24に公開中

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