3TKM

Crystal structure PPAR delta binding GW0742

Summary for 3TKM

Entry DOI	10.2210/pdb3tkm/pdb
Descriptor	Peroxisome proliferator-activated receptor delta, {4-[({2-[3-fluoro-4-(trifluoromethyl)phenyl]-4-methyl-1,3-thiazol-5-yl}methyl)sulfanyl]-2-methylphenoxy}acetic acid, GLYCEROL, ... (4 entities in total)
Functional Keywords	nuclear receptor, transcription, transcription-transcription activator complex, transcription/transcription activator
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	31994.12
Authors	Trivella, D.B.B.,Batista, F.H.,Polikarpov, I. (deposition date: 2011-08-27, release date: 2012-07-04, Last modification date: 2023-09-13)
Primary citation	Batista, F.A.,Trivella, D.B.,Bernardes, A.,Gratieri, J.,Oliveira, P.S.,Figueira, A.C.,Webb, P.,Polikarpov, I. Structural Insights into Human Peroxisome Proliferator Activated Receptor Delta (PPAR-Delta) Selective Ligand Binding. Plos One, 7:e33643-e33643, 2012 Cited by PubMed: 22606221 DOI: 10.1371/journal.pone.0033643 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.953 Å)

Structure validation