3TK5

Factor Xa in complex with D102-4380

Summary for 3TK5

• Entry DOI: 10.2210/pdb3tk5/pdb
• Related: 1V3X 1WU1 2D1J 2EI6 2EI7 2EI8 3TK6
• Descriptor: Factor X heavy chain, Factor X light chain, CALCIUM ION, ... (5 entities in total)
• Functional Keywords: glycoprotein, hydrolase, serine protease, plasma, blood, coagulation factor, calcium-binding, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Homo sapiens (human); More
• Cellular location: Secreted: P00742 P00742
• Total number of polymer chains: 2
• Total formula weight: 32800.72

Authors

Suzuki, M.,Mochizuki, A.,Nagata, T.,Takano, H.,Kanno, H.,Kishida, M.,Ohta, T. (deposition date: 2011-08-25, release date: 2012-08-29, Last modification date: 2017-11-08)

• Primary citation: Mochizuki, A.,Nagata, T.,Takano, H.,Kanno, H.,Kishida, M.,Suzuki, M.,Ohta, T.; Zwitter ionic potent durable orally active Factor Xa inhibitor.; To be Published,

Experimental method

X-RAY DIFFRACTION (2.2 Å)