3TJU

Crystal structure of human granzyme H with an inhibitor

Summary for 3TJU

• Entry DOI: 10.2210/pdb3tju/pdb
• Related: 3TJV 3TK9
• Related PRD ID: PRD_000977
• Descriptor: Granzyme H, Ac-PTSY-CMK inhibitor, SULFATE ION, ... (4 entities in total)
• Functional Keywords: serine protease, cytolysis, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Homo sapiens (human); More
• Cellular location: Cytoplasmic granule: P20718
• Total number of polymer chains: 2
• Total formula weight: 26026.63

Authors

Wang, L.,Zhang, K.,Wu, L.,Tong, L.,Sun, F.,Fan, Z. (deposition date: 2011-08-25, release date: 2011-12-28, Last modification date: 2023-12-06)

• Primary citation: Wang, L.,Zhang, K.,Wu, L.,Liu, S.,Zhang, H.,Zhou, Q.,Tong, L.,Sun, F.,Fan, Z.; Structural insights into the substrate specificity of human granzyme H: the functional roles of a novel RKR motif; J.Immunol., 188:765-773, 2012; PubMed: 22156497; DOI: 10.4049/jimmunol.1101381

Experimental method

X-RAY DIFFRACTION (2.7 Å)