3TJU
Crystal structure of human granzyme H with an inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Granzyme H | polymer | 226 | 25211.4 | 1 | UniProt (P20718) Pfam (PF00089) | Homo sapiens (human) | GzmH, CCP-X, Cathepsin G-like 2, CTSGL2, Cytotoxic T-lymphocyte proteinase, Cytotoxic serine protease C, CSP-C |
| 2 | B (B) | Ac-PTSY-CMK inhibitor | polymer | 6 | 527.0 | 1 | BIRD (PRD_000977) | ||
| 3 | C, D, E (A) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 4 | F (A) | water | water | 18.0 | 30 | Chemie (HOH) |
Sequence modifications
A: 16 - 241 (UniProt: P20718)
| PDB | External Database | Details |
|---|---|---|
| Asn 103 | Asp 108 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 25738.4 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 288.2 | |
| All* | Total formula weight | 26026.6 |
