3THD
Crystal structure of human beta-galactosidase in complex with 1-deoxygalactonojirimycin
Summary for 3THD
| Entry DOI | 10.2210/pdb3thd/pdb |
| Related | 3THC |
| Descriptor | Beta-galactosidase, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... (7 entities in total) |
| Functional Keywords | beta-galactosidase, tim-barrel domain, glycosyl hydrolase, glycosylation, hydrolase |
| Biological source | Homo sapiens (human) |
| Cellular location | Isoform 1: Lysosome. Isoform 2: Cytoplasm, perinuclear region: P16278 |
| Total number of polymer chains | 4 |
| Total formula weight | 300260.22 |
| Authors | Ohto, U.,Shimizu, T. (deposition date: 2011-08-18, release date: 2011-12-07, Last modification date: 2023-11-01) |
| Primary citation | Ohto, U.,Usui, K.,Ochi, T.,Yuki, K.,Satow, Y.,Shimizu, T. Crystal structure of human beta-galactosidase: structural basis of Gm1 gangliosidosis and morquio B diseases J.Biol.Chem., 287:1801-1812, 2012 Cited by PubMed: 22128166DOI: 10.1074/jbc.M111.293795 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.79 Å) |
Structure validation
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