3TG6
Crystal Structure of Influenza A Virus nucleoprotein with Ligand
Summary for 3TG6
Entry DOI | 10.2210/pdb3tg6/pdb |
Descriptor | Nucleocapsid protein, [4-(2-chloro-4-nitrophenyl)piperazin-1-yl][3-(2-chloropyridin-3-yl)-5-methyl-1,2-oxazol-4-yl]methanone (3 entities in total) |
Functional Keywords | influenza nucleoprotein, viral protein-inhibitor complex, viral protein/inhibitor |
Biological source | Influenza A virus |
Total number of polymer chains | 2 |
Total formula weight | 114536.67 |
Authors | Pearce, B.C.,Lewis, H.A.,McDonnell, P.A.,Steinbacher, S.,Kiefersauer, R.,Mortl, M.,Maskos, K.,Edavettal, S.,Baldwin, E.T.,Langley, D.R. (deposition date: 2011-08-17, release date: 2012-08-29, Last modification date: 2024-02-28) |
Primary citation | Edavettal, S.C.,Pearce, B.C.,Lewis, H.A.,Schneeweis, L.,Deminie, C.,Discotto, L.,Carpenter, B.,Yanchunas, J.,Langley, D.R.,Metzler, W.,Gao, M.,Poss, M.A.,Maskos, K.,Mortl, M.,Keifersauer, R.,Steinbacher, S.,Healy, M.,Phillip, T.,Zoeckler, M.,Schartman, R.,McAuliffe, B.,Minassian, B.F.,Shi, S.,Zhu, S.,Pendri, A.,Li, G.,Sinz, M.,Meanwell, N.A.,Krystal, M.,Gerritz, S.W.,Cianci, C.,Baldwin, B.T.,Bryson, J.W.,McDonnell, P.A. Biophysical and Structural Characterization of a Novel Class of Influenza Virus Inhibitors To be Published, |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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