3TBY

CRYSTAL STRUCTURE OF THE MURINE CLASS I MAJOR HISTOCOMPATIBILITY COMPLEX H-2DB IN COMPLEX WITH THE LCMV-DERIVED GP33 ALTERED PEPTIDE ligand (V3P, Y4F)

3TBY の概要

• エントリーDOI: 10.2210/pdb3tby/pdb
• 関連するPDBエントリー: 1S7U 1S7V 1S7W 1S7X 3QUK 3QUL 3TBS 3TBT 3TBV 3TBW 3tbx
• 分子名称: H-2 class I histocompatibility antigen, D-B alpha chain, Beta-2-microglobulin, GLYCOPROTEIN GPC, ... (4 entities in total)
• 機能のキーワード: murine mhc, lcmv, receptor binding, beta2-microglobulin, immune system, t cell recognition, antigen presentation, altered peptide ligand, agonism, antagonism, t cell receptor, cd8, cell surface, immune system-agonist complex, immune system/agonist
• 由来する生物種: Mus musculus (mouse); 詳細
• 細胞内の位置: Membrane; Single-pass type I membrane protein: P01899; Secreted: P01887; Stable signal peptide: Virion membrane ; Multi-pass membrane protein . Glycoprotein G1: Virion membrane ; Peripheral membrane protein . Glycoprotein G2: Virion membrane ; Single-pass membrane protein : P07399
• タンパク質・核酸の鎖数: 12
• 化学式量合計: 179277.11

構造登録者

Duru, A.D.,Allerbring, E.B.,Uchtenhagen, H.,Mazumdar, P.A.,Badia-Martinez, D.,Madhurantakam, C.,Sandalova, T.,Nygren, P.,Achour, A. (登録日: 2011-08-08, 公開日: 2012-08-08, 最終更新日: 2023-09-13)

• 主引用文献: Duru, A.D.,Allerbring, E.B.,Uchtenhagen, H.,Mazumdar, P.A.,Badia-Martinez, D.,Madhurantakam, C.,Sandalova, T.,Nygren, P.,Achour, A.; Conversion of a T cell viral antagonist into an agonist through higher stabilization and conserved molecular mimicry: Implications for TCR recognition; To be Published,

実験手法

X-RAY DIFFRACTION (2.5 Å)