3T9J

Crystal structure HP-NAP from strain YS39 in apo form

Summary for 3T9J

Entry DOI	10.2210/pdb3t9j/pdb
Related	3TA8
Descriptor	Neutrophil-activating protein, 1,2-ETHANEDIOL (3 entities in total)
Functional Keywords	dodecamer, four-helix bundle, metal transport
Biological source	Helicobacter pylori
Total number of polymer chains	1
Total formula weight	19068.69
Authors	Tsuruta, O.,Yokoyama, H.,Fujii, S. (deposition date: 2011-08-03, release date: 2012-02-08, Last modification date: 2023-11-01)
Primary citation	Tsuruta, O.,Yokoyama, H.,Fujii, S. A new crystal lattice structure of Helicobacter pylori neutrophil-activating protein (HP-NAP) Acta Crystallogr.,Sect.F, 68:134-140, 2012 Cited by PubMed Abstract: A new crystal lattice structure of Helicobacter pylori neutrophil-activating protein (HP-NAP) has been determined in two forms: the native state (Apo) at 2.20 Å resolution and an iron-loaded form (Fe-load) at 2.50 Å resolution. The highly solvated packing of the dodecameric shell is suitable for crystallographic study of the metal ion-uptake pathway. Like other bacterioferritins, HP-NAP forms a spherical dodecamer with 23 symmetry including two kinds of channels. Iron loading causes a series of conformational changes of amino-acid residues (Trp26, Asp52 and Glu56) at the ferroxidase centre. PubMed: 22297984 DOI: 10.1107/S1744309111052675 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation