3T5I

Structure of Fully modified farnesylated Rheb Peptide in complex with PDE6D

Summary for 3T5I

• Entry DOI: 10.2210/pdb3t5i/pdb
• Related: 3T5G
• Descriptor: Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta, C-terminal Farnesylated Rheb peptide CSQQGKSS(CMT), FARNESYL, ... (4 entities in total)
• Functional Keywords: immunoglobulin-like beta sandwitch fold, rheb, farnesyl, prenyl, signaling protein, lipid binding protein
• Biological source: Homo sapiens (human); More
• Cellular location: Cytoplasm, cytosol : O43924
• Total number of polymer chains: 6
• Total formula weight: 73050.05

Authors

Ismail, S.A.,Chen, Y.-X.,Wittinghofer, A. (deposition date: 2011-07-27, release date: 2011-11-02, Last modification date: 2023-09-13)

• Primary citation: Ismail, S.A.,Chen, Y.X.,Rusinova, A.,Chandra, A.,Bierbaum, M.,Gremer, L.,Triola, G.,Waldmann, H.,Bastiaens, P.I.,Wittinghofer, A.; Arl2-GTP and Arl3-GTP regulate a GDI-like transport system for farnesylated cargo.; Nat.Chem.Biol., 7:942-949, 2011; PubMed: 22002721; DOI: 10.1038/nchembio.686

Experimental method

X-RAY DIFFRACTION (2.1 Å)