3T3S
Human Cytochrome P450 2A13 in complex with Pilocarpine
Summary for 3T3S
Entry DOI | 10.2210/pdb3t3s/pdb |
Related | 2P85 3T3Q 3T3R 3T3Z |
Descriptor | Cytochrome P450 2A13, PROTOPORPHYRIN IX CONTAINING FE, (3S,4R)-3-ethyl-4-[(1-methyl-1H-imidazol-5-yl)methyl]dihydrofuran-2(3H)-one, ... (4 entities in total) |
Functional Keywords | cyp2a13, cytochrome p450 2a13, p450 2a13, heme protein, monooxygenase, drug metabolism, xenobiotic metabolism, endoplasmic reticulum, membrane, oxidoreductase |
Biological source | Homo sapiens (human) |
Cellular location | Endoplasmic reticulum membrane; Peripheral membrane protein: Q16696 |
Total number of polymer chains | 8 |
Total formula weight | 444619.50 |
Authors | DeVore, N.M.,Scott, E.E. (deposition date: 2011-07-25, release date: 2011-12-07, Last modification date: 2023-09-13) |
Primary citation | DeVore, N.M.,Meneely, K.M.,Bart, A.G.,Stephens, E.S.,Battaile, K.P.,Scott, E.E. Structural comparison of cytochromes P450 2A6, 2A13, and 2E1 with pilocarpine. Febs J., 279:1621-1631, 2012 Cited by PubMed: 22051186DOI: 10.1111/j.1742-4658.2011.08412.x PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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