3T11

Dimeric inhibitor of HIV-1 protease.

3T11 の概要

• エントリーDOI: 10.2210/pdb3t11/pdb
• 分子名称: HIV-1 Protease, (3S,11S)-11-(3-chloro-4-hydroxy-5-methoxyphenyl)-3-phenyl-2,3,4,5,10,11-hexahydro-1H-dibenzo[b,e][1,4]diazepin-1-one, CHLORIDE ION, ... (5 entities in total)
• 機能のキーワード: hiv-1 protease, beta barel, retroviral aspartyl protease, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: Human immunodeficiency virus type 1 (HIV-1)
• 細胞内の位置: Gag-Pol polyprotein: Host cell membrane ; Lipid-anchor. Matrix protein p17: Virion membrane; Lipid- anchor . Capsid protein p24: Virion . Nucleocapsid protein p7: Virion . Reverse transcriptase/ribonuclease H: Virion . Integrase: Virion : P03367
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 22693.08

構造登録者

Brynda, J.,Rezacova, P.,Saskova, G.K.,Kozisek, M.,Konvalinka, J. (登録日: 2011-07-21, 公開日: 2012-08-22, 最終更新日: 2023-09-13)

• 主引用文献: Brynda, J.,Rezacova, P.,Saskova, G.K.,Kozisek, M.,Konvalinka, J.; Dimeric inhibitor of HIV-1 protease.; To be Published,

実験手法

X-RAY DIFFRACTION (2.22 Å)