3T0E
Crystal structure of a complete ternary complex of T cell receptor, peptide-MHC and CD4
Summary for 3T0E
Entry DOI | 10.2210/pdb3t0e/pdb |
Related | 3O6F |
Descriptor | HLA class II histocompatibility antigen, DR alpha chain, HLA class II histocompatibility antigen, DRB1-4 beta chain, T-cell receptor alpha chain, ... (5 entities in total) |
Functional Keywords | cd4, t cell receptor, tcr, hla class ii, mhc, autoimmunity, t cell activation, immunoglobulin fold, immune system, membrane |
Biological source | Homo sapiens (human) More |
Cellular location | Cell membrane; Single-pass type I membrane protein: P01903 P13760 P01730 |
Total number of polymer chains | 5 |
Total formula weight | 138315.22 |
Authors | Yin, Y.,Mariuzza, R.A. (deposition date: 2011-07-20, release date: 2012-03-07, Last modification date: 2017-11-08) |
Primary citation | Yin, Y.,Wang, X.X.,Mariuzza, R.A. Crystal structure of a complete ternary complex of T-cell receptor, peptide-MHC, and CD4. Proc.Natl.Acad.Sci.USA, 109:5405-5410, 2012 Cited by PubMed: 22431638DOI: 10.1073/pnas.1118801109 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (4 Å) |
Structure validation
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