3SVH
Crystal Structure of the bromdomain of human CREBBP in complex with a 3,5-dimethylisoxazol ligand
Summary for 3SVH
Entry DOI | 10.2210/pdb3svh/pdb |
Related | 3SVF 3SVG |
Descriptor | CREB-binding protein, 3-(3,5-dimethyl-1,2-oxazol-4-yl)-5-ethoxybenzoic acid, 1,2-ETHANEDIOL, ... (4 entities in total) |
Functional Keywords | isoxazole, bromodomain, structural genomics, structural genomics consortium, sgc, unknown function |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: Q92793 |
Total number of polymer chains | 2 |
Total formula weight | 29553.86 |
Authors | Filippakopoulos, P.,Picaud, S.,Felletar, I.,Hewings, S.D.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Weigelt, J.,Bountra, C.,Conway, S.J.,Knapp, S.,Structural Genomics Consortium (SGC) (deposition date: 2011-07-12, release date: 2011-08-10, Last modification date: 2023-09-13) |
Primary citation | Filippakopoulos, P.,Picaud, S.,Felletar, I.,Hewings, S.D.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Weigelt, J.,Bountra, C.,Conway, S.J.,Knapp, S. Crystal Structure of the bromdomain of human CREBBP in complex with a 3,5-dimethylisoxazol ligand To be Published, |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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