3SVH

Crystal Structure of the bromdomain of human CREBBP in complex with a 3,5-dimethylisoxazol ligand

3SVH の概要

• エントリーDOI: 10.2210/pdb3svh/pdb
• 関連するPDBエントリー: 3SVF 3SVG
• 分子名称: CREB-binding protein, 3-(3,5-dimethyl-1,2-oxazol-4-yl)-5-ethoxybenzoic acid, 1,2-ETHANEDIOL, ... (4 entities in total)
• 機能のキーワード: isoxazole, bromodomain, structural genomics, structural genomics consortium, sgc, unknown function
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Cytoplasm: Q92793
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 29553.86

構造登録者

Filippakopoulos, P.,Picaud, S.,Felletar, I.,Hewings, S.D.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Weigelt, J.,Bountra, C.,Conway, S.J.,Knapp, S.,Structural Genomics Consortium (SGC) (登録日: 2011-07-12, 公開日: 2011-08-10, 最終更新日: 2023-09-13)

• 主引用文献: Filippakopoulos, P.,Picaud, S.,Felletar, I.,Hewings, S.D.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Weigelt, J.,Bountra, C.,Conway, S.J.,Knapp, S.; Crystal Structure of the bromdomain of human CREBBP in complex with a 3,5-dimethylisoxazol ligand; To be Published,

実験手法

X-RAY DIFFRACTION (1.8 Å)