3SS5

Crystal structure of mouse Glutaminase C, L-glutamate-bound form

Summary for 3SS5

• Entry DOI: 10.2210/pdb3ss5/pdb
• Related: 3SS3 3SS4
• Descriptor: Glutaminase C, GLUTAMIC ACID (3 entities in total)
• Functional Keywords: glutaminase, l-glutamine, mitochondria, catalysis product, hydrolase
• Biological source: Mus musculus (mouse)
• Total number of polymer chains: 4
• Total formula weight: 213896.36

Authors

Ambrosio, A.L.B.,Dias, S.M.G.,Cerione, R.A. (deposition date: 2011-07-07, release date: 2012-01-11, Last modification date: 2023-09-13)

• Primary citation: Cassago, A.,Ferreira, A.P.,Ferreira, I.M.,Fornezari, C.,Gomes, E.R.,Greene, K.S.,Pereira, H.M.,Garratt, R.C.,Dias, S.M.,Ambrosio, A.L.; Mitochondrial localization and structure-based phosphate activation mechanism of Glutaminase C with implications for cancer metabolism.; Proc.Natl.Acad.Sci.USA, 109:1092-1097, 2012; PubMed: 22228304; DOI: 10.1073/pnas.1112495109

Experimental method

X-RAY DIFFRACTION (2.8 Å)