3SN5

Crystal structure of human CYP7A1 in complex with cholest-4-en-3-one

3SN5 の概要

• エントリーDOI: 10.2210/pdb3sn5/pdb
• 分子名称: Cholesterol 7-alpha-monooxygenase, PROTOPORPHYRIN IX CONTAINING FE, (8ALPHA,9BETA)-CHOLEST-4-EN-3-ONE, ... (5 entities in total)
• 機能のキーワード: cytochrome p450, cholesterol 7-alpha hydroxylase, cyp7a1, cholest-4-en-3-one, bile acid biosynthesis, structural genomics, structural genomics consortium, sgc, oxidoreductase
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Endoplasmic reticulum membrane; Peripheral membrane protein: P22680
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 114965.92

構造登録者

Strushkevich, N.,Tempel, W.,MacKenzie, F.,Wernimont, A.K.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Weigelt, J.,Park, H.,Structural Genomics Consortium (SGC) (登録日: 2011-06-28, 公開日: 2011-07-13, 最終更新日: 2023-09-13)

• 主引用文献: Strushkevich, N.,Tempel, W.,MacKenzie, F.,Wernimont, A.K.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Weigelt, J.,Park, H.; Crystal structure of human CYP7A1 in complex with cholest-4-en-3-one; To be Published,

実験手法

X-RAY DIFFRACTION (2.75 Å)