3SM4

Crystal Structure of the K131A Mutant of Lambda Exonuclease in Complex with a 5'-Phosphorylated 14-mer/12-mer Duplex and Magnesium

3SM4 の概要

• エントリーDOI: 10.2210/pdb3sm4/pdb
• 関連するPDBエントリー: 3SLP
• 分子名称: Exonuclease, 5'-D(*TP*CP*GP*GP*TP*AP*CP*AP*GP*TP*AP*G)-3', 5'-D(P*AP*GP*CP*TP*AP*CP*TP*GP*TP*AP*CP*CP*GP*A)-3', ... (7 entities in total)
• 機能のキーワード: homologous recombination, dna repair, recombineering, single-strand annealing, type ii restriction endonuclease fold, 5'-3' dsdna exonuclease, hydrolase-dna complex, hydrolase/dna
• 由来する生物種: Enterobacteria phage lambda
• タンパク質・核酸の鎖数: 5
• 化学式量合計: 86770.95

構造登録者

Bell, C.E.,Zhang, J. (登録日: 2011-06-27, 公開日: 2011-07-20, 最終更新日: 2023-09-13)

• 主引用文献: Zhang, J.,McCabe, K.A.,Bell, C.E.; Crystal structures of {lambda} exonuclease in complex with DNA suggest an electrostatic ratchet mechanism for processivity.; Proc.Natl.Acad.Sci.USA, 108:11872-11877, 2011; PubMed: 21730170; DOI: 10.1073/pnas.1103467108

実験手法

X-RAY DIFFRACTION (1.88 Å)