3SIO

Ac-AChBP ligand binding domain (not including beta 9-10 linker) mutated to human alpha-7 nAChR

3SIO の概要

• エントリーDOI: 10.2210/pdb3sio/pdb
• 関連するPDBエントリー: 2BYR 3SH1 3T4M
• 分子名称: Soluble acetylcholine receptor, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (9 entities in total)
• 機能のキーワード: mutated acetylcholine binding protein, aplysia californica, alpha-7 human nicotinic acetylcholine receptor, achbp, nachr, binding protein, acetylcholine, glycosylation, receptor, methyllycaconitine
• 由来する生物種: Aplysia californica (California sea hare)
• タンパク質・核酸の鎖数: 10
• 化学式量合計: 277709.07

構造登録者

Nemecz, A.,Taylor, P.W. (登録日: 2011-06-19, 公開日: 2011-10-26, 最終更新日: 2024-04-03)

• 主引用文献: Nemecz, A.,Taylor, P.; Creating an alpha-7 nicotinic acetylcholine recognition domain from the acetylcholine binding protein: crystallographic and ligand selectivity analyses; J.Biol.Chem., 286:42555-42565, 2011; PubMed: 22009746; DOI: 10.1074/jbc.M111.286583

実験手法

X-RAY DIFFRACTION (2.32 Å)