3SFV

Crystal structure of the GDP-bound Rab1a S25N mutant in complex with the coiled-coil domain of LidA from Legionella pneumophila

3SFV の概要

• エントリーDOI: 10.2210/pdb3sfv/pdb
• 分子名称: Ras-related protein Rab-1A, LidA protein, substrate of the Dot/Icm system, GUANOSINE-5'-DIPHOSPHATE, ... (4 entities in total)
• 機能のキーワード: lida-rab complex, coiled-coil domain, type iv effector protein from legionella, gdp binding, protein transport-protein binding complex, protein transport/protein binding
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Golgi apparatus: P62820
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 61110.98

構造登録者

Yin, K.,Lu, D.,Zhu, D.,Zhang, H.,Li, B.,Xu, S.,Gu, L. (登録日: 2011-06-14, 公開日: 2012-04-18, 最終更新日: 2023-11-01)

• 主引用文献: Cheng, W.,Yin, K.,Lu, D.,Li, B.,Zhu, D.,Chen, Y.,Zhang, H.,Xu, S.,Chai, J.,Gu, L.; Structural Insights into a Unique Legionella pneumophila Effector LidA Recognizing Both GDP and GTP Bound Rab1 in Their Active State; Plos Pathog., 8:e1002528-e1002528, 2012; PubMed: 22416225; DOI: 10.1371/journal.ppat.1002528

実験手法

X-RAY DIFFRACTION (1.73 Å)