3SE6

Crystal structure of the human Endoplasmic Reticulum Aminopeptidase 2

3SE6 の概要

• エントリーDOI: 10.2210/pdb3se6/pdb
• 分子名称: Endoplasmic reticulum aminopeptidase 2, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-4)-alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total)
• 機能のキーワード: thermolysin-like catalytic domain, aminopeptidase, zinc binding, glycosylation, endoplasmic reticulum, hydrolase
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 226107.54

構造登録者

Birtley, J.R.,Saridakis, E.,Stratikos, E.,Mavridis, I.M. (登録日: 2011-06-10, 公開日: 2011-12-21, 最終更新日: 2020-07-29)

• 主引用文献: Birtley, J.R.,Saridakis, E.,Stratikos, E.,Mavridis, I.M.; The crystal structure of human endoplasmic reticulum aminopeptidase 2 reveals the atomic basis for distinct roles in antigen processing.; Biochemistry, 51:286-295, 2012; PubMed: 22106953; DOI: 10.1021/bi201230p

実験手法

X-RAY DIFFRACTION (3.08 Å)