3SD0

Identification of a Glycogen Synthase Kinase-3b Inhibitor that Attenuates Hyperactivity in CLOCK Mutant Mice

Summary for 3SD0

• Entry DOI: 10.2210/pdb3sd0/pdb
• Descriptor: Glycogen synthase kinase-3 beta, 3-(5-fluoro-6-iodo-1-methyl-1H-indol-3-yl)-4-(7-methoxy-1-benzofuran-3-yl)-1H-pyrrole-2,5-dione, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... (4 entities in total)
• Functional Keywords: kinase, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm: P49841
• Total number of polymer chains: 2
• Total formula weight: 81114.72

Authors

Mesecar, A.M.,Walters, R.L. (deposition date: 2011-06-08, release date: 2011-08-03, Last modification date: 2024-02-28)

• Primary citation: Mesecar, A.M.,Walters, R.L.; Identification of a Glycogen Synthase Kinase-3b Inhibitor that Attenuates Hyperactivity in CLOCK Mutant Mice; To be Published,

Experimental method

X-RAY DIFFRACTION (2.7 Å)