3SD0
Identification of a Glycogen Synthase Kinase-3b Inhibitor that Attenuates Hyperactivity in CLOCK Mutant Mice
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Glycogen synthase kinase-3 beta | polymer | 350 | 39802.8 | 2 | UniProt (P49841) Pfam (PF00069) | Homo sapiens (human) | GSK-3 beta |
| 2 | C, E (A, B) | 3-(5-fluoro-6-iodo-1-methyl-1H-indol-3-yl)-4-(7-methoxy-1-benzofuran-3-yl)-1H-pyrrole-2,5-dione | non-polymer | 516.3 | 2 | Chemie (TSK) | |||
| 3 | D, F (A, B) | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | non-polymer | 238.3 | 2 | Chemie (EPE) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 284 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 79605.6 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1509.1 | |
| All* | Total formula weight | 81114.7 |
