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3SD0

Identification of a Glycogen Synthase Kinase-3b Inhibitor that Attenuates Hyperactivity in CLOCK Mutant Mice

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, BGlycogen synthase kinase-3 betapolymer35039802.82UniProt (P49841)
Pfam (PF00069)
In PDB
Homo sapiens (human)GSK-3 beta
2A, B3-(5-fluoro-6-iodo-1-methyl-1H-indol-3-yl)-4-(7-methoxy-1-benzofuran-3-yl)-1H-pyrrole-2,5-dionenon-polymer516.32Chemie (TSK)
3A, B4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACIDnon-polymer238.32Chemie (EPE)
4waterwater18.0284Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight79605.6
Non-Polymers*Number of molecules4
Total formula weight1509.1
All*Total formula weight81114.7
*Water molecules are not included.

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PDB entries from 2024-07-24

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