3S9U
Bacillus anthracis Dihydrofolate Reductase bound to propargyl-linked TMP analog, UCP120J
Summary for 3S9U
Entry DOI | 10.2210/pdb3s9u/pdb |
Related | 3E0B 3JVX 3JWC 3JWF 3JWK 3JWM 3SA1 3SA2 3SAI |
Descriptor | Dihydrofolate reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 6-ethyl-5-[3-(4-methoxybiphenyl-3-yl)prop-1-yn-1-yl]pyrimidine-2,4-diamine, ... (4 entities in total) |
Functional Keywords | oxidoreductase |
Biological source | Bacillus anthracis (anthrax,anthrax bacterium) |
Total number of polymer chains | 2 |
Total formula weight | 41418.34 |
Authors | Anderson, A.C.,Beierlein, J.M. (deposition date: 2011-06-02, release date: 2012-06-13, Last modification date: 2023-09-13) |
Primary citation | Anderson, A.C.,Beierlein, J.M.,Viswanathan, K.,Wright, D.L. Structure-Activity Studies of Heterocyclic Propargyl-linked TMP Analogs Targeting Bacillus anthracis Dihydrofolate Reductase To be Published, |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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