3S95

Crystal structure of the human LIMK1 kinase domain in complex with staurosporine

3S95 の概要

• エントリーDOI: 10.2210/pdb3s95/pdb
• 分子名称: LIM domain kinase 1, STAUROSPORINE, SODIUM ION, ... (8 entities in total)
• 機能のキーワード: structural genomics, structural genomics consortium, sgc, protein kinase, lim domain kinase, transferase-antibiotic complex, transferase/antibiotic
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Cytoplasm: P53667
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 74414.99

構造登録者

Beltrami, A.,Chaikuad, A.,Daga, N.,Elkins, J.M.,Mahajan, P.,Savitsky, P.,Vollmar, M.,Krojer, T.,Muniz, J.R.C.,Fedorov, O.,Allerston, C.K.,Yue, W.W.,Gileadi, O.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Weigelt, J.,Bountra, C.,Knapp, S.,Bullock, A.,Structural Genomics Consortium (SGC) (登録日: 2011-05-31, 公開日: 2011-07-06, 最終更新日: 2023-09-13)

• 主引用文献: Beltrami, A.,Chaikuad, A.,Daga, N.,Elkins, J.M.,Mahajan, P.,Savitsky, P.,Vollmar, M.,Krojer, T.,Muniz, J.R.C.,Fedorov, O.,Allerston, C.K.,Yue, W.W.,Gileadi, O.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Weigelt, J.,Bountra, C.,Knapp, S.,Bullock, A.; Crystal structure of the human LIMK1 kinase domain in complex with staurosporine; To be Published,

実験手法

X-RAY DIFFRACTION (1.65 Å)