3S8P
Crystal Structure of the SET Domain of Human Histone-Lysine N-Methyltransferase SUV420H1 In Complex With S-Adenosyl-L-Methionine
Summary for 3S8P
Entry DOI | 10.2210/pdb3s8p/pdb |
Descriptor | Histone-lysine N-methyltransferase SUV420H1, ZINC ION, S-ADENOSYLMETHIONINE, ... (4 entities in total) |
Functional Keywords | set domain, histone methyltransferase, transcription regulation, histone lysine, sam, methylation, nucleus, chromosome, structural genomics, structural genomics consortium, sgc, transferase |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus : Q4FZB7 |
Total number of polymer chains | 2 |
Total formula weight | 64689.94 |
Authors | Lam, R.,Zeng, H.,Loppnau, P.,Bountra, C.,Weigelt, J.,Arrowsmith, C.H.,Edwards, A.M.,Min, J.,Wu, H.,Structural Genomics Consortium (SGC) (deposition date: 2011-05-30, release date: 2011-07-06, Last modification date: 2017-11-08) |
Primary citation | Wu, H.,Siarheyeva, A.,Zeng, H.,Lam, R.,Dong, A.,Wu, X.H.,Li, Y.,Schapira, M.,Vedadi, M.,Min, J. Crystal structures of the human histone H4K20 methyltransferases SUV420H1 and SUV420H2. Febs Lett., 587:3859-3868, 2013 Cited by PubMed: 24396869PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.85 Å) |
Structure validation
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