3S8P
Crystal Structure of the SET Domain of Human Histone-Lysine N-Methyltransferase SUV420H1 In Complex With S-Adenosyl-L-Methionine
3S8P の概要
エントリーDOI | 10.2210/pdb3s8p/pdb |
分子名称 | Histone-lysine N-methyltransferase SUV420H1, ZINC ION, S-ADENOSYLMETHIONINE, ... (4 entities in total) |
機能のキーワード | set domain, histone methyltransferase, transcription regulation, histone lysine, sam, methylation, nucleus, chromosome, structural genomics, structural genomics consortium, sgc, transferase |
由来する生物種 | Homo sapiens (human) |
細胞内の位置 | Nucleus : Q4FZB7 |
タンパク質・核酸の鎖数 | 2 |
化学式量合計 | 64689.94 |
構造登録者 | Lam, R.,Zeng, H.,Loppnau, P.,Bountra, C.,Weigelt, J.,Arrowsmith, C.H.,Edwards, A.M.,Min, J.,Wu, H.,Structural Genomics Consortium (SGC) (登録日: 2011-05-30, 公開日: 2011-07-06, 最終更新日: 2017-11-08) |
主引用文献 | Wu, H.,Siarheyeva, A.,Zeng, H.,Lam, R.,Dong, A.,Wu, X.H.,Li, Y.,Schapira, M.,Vedadi, M.,Min, J. Crystal structures of the human histone H4K20 methyltransferases SUV420H1 and SUV420H2. Febs Lett., 587:3859-3868, 2013 Cited by PubMed: 24396869主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (1.85 Å) |
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