3RXB

Crystal structure of Trypsin complexed with 4-guanidinobutanoic acid

Summary for 3RXB

Related3RXA 3RXC 3RXD 3RXE 3RXF 3RXG 3RXH 3RXI 3RXJ 3RXK 3RXL 3RXM 3RXO 3RXP 3RXQ 3RXR 3RXS 3RXT 3RXU 3RXV 3ATI 3ATK 3ATL 3ATM
DescriptorCationic trypsin, CALCIUM ION, GLYCEROL, ... (6 entities in total)
Functional Keywordstrypsin-like serine proteases, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological sourceBos taurus (bovine)
Cellular locationSecreted, extracellular space P00760
Total number of polymer chains1
Total molecular weight23849.98
Authors
Yamane, J.,Yao, M.,Zhou, Y.,Tanaka, I. (deposition date: 2011-05-10, release date: 2011-08-24)
Primary citation
Yamane, J.,Yao, M.,Zhou, Y.,Hiramatsu, Y.,Fujiwara, K.,Yamaguchi, T.,Yamaguchi, H.,Togame, H.,Tsujishita, H.,Takemoto, H.,Tanaka, I.
In-crystal affinity ranking of fragment hit compounds reveals a relationship with their inhibitory activities
J.Appl.Crystallogr., 44:798-804, 2011
DOI: 10.1107/S0021889811017717
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.7 Å)
?

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.1703001.8%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 3rxb
no rotation
Molmil generated image of 3rxb
rotated about x axis by 90°
Molmil generated image of 3rxb
rotated about y axis by 90°