3RVH

Crystal Structure of JMJD2A Complexed with Inhibitor

3RVH の概要

• エントリーDOI: 10.2210/pdb3rvh/pdb
• 関連するPDBエントリー: 2OQ7 2OX0 2VD7 2WWJ 3NJY 3PDQ
• 分子名称: Lysine-specific demethylase 4A, NICKEL (II) ION, ZINC ION, ... (6 entities in total)
• 機能のキーワード: oxidoreductase, jmjc domain, chromatin regulator, dioxygenase, transcription, iron, 2-oxoglutarate, alpha-ketoglutarate, demethylation, nucleus, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Nucleus : O75164
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 89631.51

構造登録者

King, O.N.F.,Maloney, D.J.,Tumber, A.,Rai, G.,Jadhav, A.,Clifton, I.J.,Heightman, T.D.,Simeonov, A.,McDonough, M.A.,Schofield, C.J. (登録日: 2011-05-06, 公開日: 2012-05-09, 最終更新日: 2023-09-13)

• 主引用文献: King, O.N.F.,Maloney, D.J.,Tumber, A.,Rai, G.,Jadhav, A.,Clifton, I.J.,Heightman, T.D.,Simeonov, A.,McDonough, M.A.,Schofield, C.J.; Crystal Structure of JMJD2A Complexed with Inhibitor; To be Published,

実験手法

X-RAY DIFFRACTION (2.251 Å)