Crystal structure of S-adenosylmethionine synthetase from Mycobacterium marinum

Summary for 3RV2

DescriptorS-adenosylmethionine synthase, CALCIUM ION, 1,2-ETHANEDIOL, ... (5 entities in total)
Functional Keywordsstructural genomics, seattle structural genomics center for infectious disease, ssgcid, sam, s-adenosylmethionine, adomet, adomet synthase, methyl donor, methylation, transferase
Biological sourceMycobacterium marinum M
Cellular locationCytoplasm  B2HP50
Total number of polymer chains2
Total molecular weight87418.68
Seattle Structural Genomics Center for Infectious Disease (SSGCID) (deposition date: 2011-05-05, release date: 2011-05-18, Last modification date: 2015-04-22)
Primary citation
Baugh, L.,Phan, I.,Begley, D.W.,Clifton, M.C.,Armour, B.,Dranow, D.M.,Taylor, B.M.,Muruthi, M.M.,Abendroth, J.,Fairman, J.W.,Fox, D.,Dieterich, S.H.,Staker, B.L.,Gardberg, A.S.,Choi, R.,Hewitt, S.N.,Napuli, A.J.,Myers, J.,Barrett, L.K.,Zhang, Y.,Ferrell, M.,Mundt, E.,Thompkins, K.,Tran, N.,Lyons-Abbott, S.,Abramov, A.,Sekar, A.,Serbzhinskiy, D.,Lorimer, D.,Buchko, G.W.,Stacy, R.,Stewart, L.J.,Edwards, T.E.,Van Voorhis, W.C.,Myler, P.J.
Increasing the structural coverage of tuberculosis drug targets.
Tuberculosis (Edinb), 95:142-148, 2015
PubMed: 25613812 (PDB entries with the same primary citation)
DOI: 10.1016/j.tube.2014.12.003
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.196101.2%0.5%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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