3RUM

New strategy to analyze structures of glycopeptide antibiotic-target complexes

3RUM の概要

• エントリーDOI: 10.2210/pdb3rum/pdb
• 関連するPDBエントリー: 1ANF 3RUL 3RUN 3VFJ 3VFK
• 関連するBIRD辞書のPRD_ID: PRD_900001
• 分子名称: Maltose-binding periplasmic protein, Ristocetin, alpha-D-arabinofuranose-(1-2)-alpha-D-mannopyranose-(1-2)-[alpha-L-rhamnopyranose-(1-6)]beta-D-glucopyranose, ... (9 entities in total)
• 機能のキーワード: antibiotic, glycopeptide, native protein ligation, fusion, carboxymethylation of cysteine, ristocetin, sugar binding protein-antibiotic complex, sugar binding protein/antibiotic
• 由来する生物種: Escherichia coli K-12; 詳細
• 細胞内の位置: Periplasm: P0AEX9
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 46509.67

構造登録者

Economou, N.J.,Weeks, S.D.,Grasty, K.C.,Nahoum, V.,Loll, P.J. (登録日: 2011-05-05, 公開日: 2012-06-06, 最終更新日: 2023-12-06)

• 主引用文献: Economou, N.J.,Nahoum, V.,Weeks, S.D.,Grasty, K.C.,Zentner, I.J.,Townsend, T.M.,Bhuiya, M.W.,Cocklin, S.,Loll, P.J.; A carrier protein strategy yields the structure of dalbavancin.; J.Am.Chem.Soc., 134:4637-4645, 2012; PubMed: 22352468; DOI: 10.1021/ja208755j

実験手法

X-RAY DIFFRACTION (1.851 Å)