3RU8

Structure of an HIV epitope scaffold in complex with neutralizing antibody b12 Fab

3RU8 の概要

• エントリーDOI: 10.2210/pdb3ru8/pdb
• 分子名称: Epitope Scaffold 2bodx43, Antibody b12, Heavy Chain, Antibody b12, Light Chain, ... (5 entities in total)
• 機能のキーワード: binding epitope from hiv on a heterologous protein, immune system, de novo protein
• 由来する生物種: Human immunodeficiency virus, synthetic construct, Thermomonospora fusca; 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 79057.90

構造登録者

Carrico, C.T.D.,Strong, R.K. (登録日: 2011-05-04, 公開日: 2011-11-02, 最終更新日: 2023-09-13)

• 主引用文献: Azoitei, M.L.,Correia, B.E.,Ban, Y.E.,Carrico, C.,Kalyuzhniy, O.,Chen, L.,Schroeter, A.,Huang, P.S.,McLellan, J.S.,Kwong, P.D.,Baker, D.,Strong, R.K.,Schief, W.R.; Computation-guided backbone grafting of a discontinuous motif onto a protein scaffold.; Science, 334:373-376, 2011; PubMed: 22021856; DOI: 10.1126/science.1209368

実験手法

X-RAY DIFFRACTION (2.07 Å)