3RU0

Cocrystal structure of human SMYD3 with inhibitor Sinefungin bound

3RU0 の概要

• エントリーDOI: 10.2210/pdb3ru0/pdb
• 分子名称: SET and MYND domain-containing protein 3, SINEFUNGIN, ZINC ION, ... (4 entities in total)
• 機能のキーワード: methyltransferase, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Cytoplasm: Q9H7B4
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 101853.99

構造登録者

Foreman, K.W.,Brown, M.,Park, F.,Emtage, S.,Harriss, J.,Das, C.,Zhu, L.,Crew, A.,Arnold, L.,Shaaban, S.,Tucker, P. (登録日: 2011-05-04, 公開日: 2011-05-18, 最終更新日: 2024-02-28)

• 主引用文献: Foreman, K.W.,Brown, M.,Park, F.,Emtage, S.,Harriss, J.,Das, C.,Zhu, L.,Crew, A.,Arnold, L.,Shaaban, S.,Tucker, P.; Structural and Functional Profiling of the Human Histone Methyltransferase SMYD3.; Plos One, 6:e22290-e22290, 2011; PubMed: 21779408; DOI: 10.1371/journal.pone.0022290

実験手法

X-RAY DIFFRACTION (1.849 Å)