3RPS
Structure of human CK2alpha in complex with the ATP-competitive inhibitor 3-(4,5,6,7-tetrabromo-1H-benzotriazol-1-yl)propan-1-ol
Summary for 3RPS
Entry DOI | 10.2210/pdb3rps/pdb |
Related | 1JWH 3OFM 3RP0 |
Descriptor | Casein kinase II subunit alpha, 3-(4,5,6,7-tetrabromo-1H-benzotriazol-1-yl)propan-1-ol, SULFATE ION, ... (5 entities in total) |
Functional Keywords | eukaryotic protein kinase fold, atp ck2beta, phosphorylation, cytoplasm nucleus, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 80960.21 |
Authors | Bischoff, N.,Raaf, J.,Olsen, B.,Bretner, M.,Issinger, O.-G.,Niefind, K. (deposition date: 2011-04-27, release date: 2011-06-08, Last modification date: 2024-02-28) |
Primary citation | Bischoff, N.,Raaf, J.,Olsen, B.,Bretner, M.,Issinger, O.G.,Niefind, K. Enzymatic activity with an incomplete catalytic spine - insights from a comparative structural analysis of human CK2alpha and its paralogous isoform CK2alpha' Mol.Cell.Biochem., 356:57-65, 2011 Cited by PubMed: 21739153DOI: 10.1007/s11010-011-0948-5 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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