3RPS

Structure of human CK2alpha in complex with the ATP-competitive inhibitor 3-(4,5,6,7-tetrabromo-1H-benzotriazol-1-yl)propan-1-ol

3RPS の概要

• エントリーDOI: 10.2210/pdb3rps/pdb
• 関連するPDBエントリー: 1JWH 3OFM 3RP0
• 分子名称: Casein kinase II subunit alpha, 3-(4,5,6,7-tetrabromo-1H-benzotriazol-1-yl)propan-1-ol, SULFATE ION, ... (5 entities in total)
• 機能のキーワード: eukaryotic protein kinase fold, atp ck2beta, phosphorylation, cytoplasm nucleus, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 80960.21

構造登録者

Bischoff, N.,Raaf, J.,Olsen, B.,Bretner, M.,Issinger, O.-G.,Niefind, K. (登録日: 2011-04-27, 公開日: 2011-06-08, 最終更新日: 2024-02-28)

• 主引用文献: Bischoff, N.,Raaf, J.,Olsen, B.,Bretner, M.,Issinger, O.G.,Niefind, K.; Enzymatic activity with an incomplete catalytic spine - insights from a comparative structural analysis of human CK2alpha and its paralogous isoform CK2alpha'; Mol.Cell.Biochem., 356:57-65, 2011; PubMed: 21739153; DOI: 10.1007/s11010-011-0948-5

実験手法

X-RAY DIFFRACTION (2.3 Å)