3RNM

The crystal structure of the subunit binding of human dihydrolipoamide transacylase (E2b) bound to human dihydrolipoamide dehydrogenase (E3)

Summary for 3RNM

Entry DOI	10.2210/pdb3rnm/pdb
Descriptor	Dihydrolipoyl dehydrogenase, mitochondrial, Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial, BETA-MERCAPTOETHANOL, ... (6 entities in total)
Functional Keywords	protein-protein interaction, redox protein, mitochondrion, oxidoreductase-protein binding complex, oxidoreductase/protein binding
Biological source	Homo sapiens (human) More
Cellular location	Mitochondrion matrix: P09622 P11182
Total number of polymer chains	6
Total formula weight	228077.49
Authors	Brautigam, C.A.,Wynn, R.M.,Chuang, J.C.,Young, B.B.,Chuang, D.T. (deposition date: 2011-04-22, release date: 2011-05-04, Last modification date: 2011-07-20)
Primary citation	Brautigam, C.A.,Wynn, R.M.,Chuang, J.L.,Naik, M.T.,Young, B.B.,Huang, T.H.,Chuang, D.T. Structural and Thermodynamic Basis for Weak Interactions between Dihydrolipoamide Dehydrogenase and Subunit-binding Domain of the Branched-chain {alpha}-Ketoacid Dehydrogenase Complex. J.Biol.Chem., 286:23476-23488, 2011 Cited by PubMed: 21543315 DOI: 10.1074/jbc.M110.202960 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.4 Å)

Structure validation