3RNM

The crystal structure of the subunit binding of human dihydrolipoamide transacylase (E2b) bound to human dihydrolipoamide dehydrogenase (E3)

3RNM の概要

• エントリーDOI: 10.2210/pdb3rnm/pdb
• 分子名称: Dihydrolipoyl dehydrogenase, mitochondrial, Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial, BETA-MERCAPTOETHANOL, ... (6 entities in total)
• 機能のキーワード: protein-protein interaction, redox protein, mitochondrion, oxidoreductase-protein binding complex, oxidoreductase/protein binding
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Mitochondrion matrix: P09622 P11182
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 228077.49

構造登録者

Brautigam, C.A.,Wynn, R.M.,Chuang, J.C.,Young, B.B.,Chuang, D.T. (登録日: 2011-04-22, 公開日: 2011-05-04, 最終更新日: 2011-07-20)

• 主引用文献: Brautigam, C.A.,Wynn, R.M.,Chuang, J.L.,Naik, M.T.,Young, B.B.,Huang, T.H.,Chuang, D.T.; Structural and Thermodynamic Basis for Weak Interactions between Dihydrolipoamide Dehydrogenase and Subunit-binding Domain of the Branched-chain {alpha}-Ketoacid Dehydrogenase Complex.; J.Biol.Chem., 286:23476-23488, 2011; PubMed: 21543315; DOI: 10.1074/jbc.M110.202960

実験手法

X-RAY DIFFRACTION (2.4 Å)