3RJF

Ternary complex of DNA Polymerase Beta with a gapped DNA containing (syn)8odG at template position paired with non-hydrolyzable dATP analog (dApCPP)

Summary for 3RJF

Related3RJE 3RJG 3RJH 3RJI 3RJJ 3RJK
DescriptorDNA polymerase beta, DNA (5'-D(*CP*CP*GP*AP*CP*(8OG)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), ... (9 entities in total)
Functional Keywordsmutagenesis, g-t transversion, dna polymerase, oxidative damage, transferase, lyase-dna complex, lyase/dna
Biological sourceHomo sapiens (human)
Cellular locationNucleus P06746
Total number of polymer chains4
Total molecular weight48448.49
Authors
Batra, V.K.,Beard, W.A.,Wilson, S.H. (deposition date: 2011-04-15, release date: 2012-01-18)
Primary citation
Batra, V.K.,Shock, D.D.,Beard, W.A.,McKenna, C.E.,Wilson, S.H.
Binary complex crystal structure of DNA polymerase beta reveals multiple conformations of the templating 8-oxoguanine lesion
Proc.Natl.Acad.Sci.USA, 109:113-118, 2012
PubMed: 22178760 (PDB entries with the same primary citation)
DOI: 10.1073/pnas.1112235108
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.3 Å)
NMR Information
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.258801.4%5.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution