3RJF
Ternary complex of DNA Polymerase Beta with a gapped DNA containing (syn)8odG at template position paired with non-hydrolyzable dATP analog (dApCPP)
Summary for 3RJF
Entry DOI | 10.2210/pdb3rjf/pdb |
Related | 3RJE 3RJG 3RJH 3RJI 3RJJ 3RJK |
Descriptor | DNA polymerase beta, DNA (5'-D(*CP*CP*GP*AP*CP*(8OG)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), ... (9 entities in total) |
Functional Keywords | mutagenesis, g-t transversion, dna polymerase, oxidative damage, transferase, lyase-dna complex, lyase/dna |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus: P06746 |
Total number of polymer chains | 4 |
Total formula weight | 48448.49 |
Authors | Batra, V.K.,Beard, W.A.,Wilson, S.H. (deposition date: 2011-04-15, release date: 2012-01-18, Last modification date: 2023-09-13) |
Primary citation | Batra, V.K.,Shock, D.D.,Beard, W.A.,McKenna, C.E.,Wilson, S.H. Binary complex crystal structure of DNA polymerase beta reveals multiple conformations of the templating 8-oxoguanine lesion Proc.Natl.Acad.Sci.USA, 109:113-118, 2012 Cited by PubMed: 22178760DOI: 10.1073/pnas.1112235108 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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