3RIA

C. elegans glutamate-gated chloride channel (GluCl) in complex with Fab, ivermectin and iodide.

Summary for 3RIA

• Entry DOI: 10.2210/pdb3ria/pdb
• Related: 3RHW 3RI5 3RIF
• Descriptor: Avermectin-sensitive glutamate-gated chloride channel GluCl alpha, Mouse monoclonal Fab fragment, heavy chain, Mouse monoclonal Fab fragment, light chain, ... (9 entities in total)
• Functional Keywords: membrane protein, transport protein, cys-loop receptor, ligand-gated ion channel, neurotransmitter receptor, ivermectin, picrotoxin, glycosylation, transport protein-immune system complex, transport protein/immune system
• Biological source: Caenorhabditis elegans (nematode); More
• Total number of polymer chains: 15
• Total formula weight: 437832.02

Authors

Hibbs, R.E.,Gouaux, E. (deposition date: 2011-04-13, release date: 2011-05-25, Last modification date: 2023-09-13)

• Primary citation: Hibbs, R.E.,Gouaux, E.; Principles of activation and permeation in an anion-selective Cys-loop receptor.; Nature, 474:54-60, 2011; PubMed: 21572436; DOI: 10.1038/nature10139

Experimental method

X-RAY DIFFRACTION (3.8 Å)