3RGV

A single TCR bound to MHCI and MHC II reveals switchable TCR conformers

3RGV の概要

• エントリーDOI: 10.2210/pdb3rgv/pdb
• 分子名称: Yae62 TCR a chain, Yae62 TCR b chain, H-2 class I histocompatibility antigen, K-B alpha chain, ... (5 entities in total)
• 機能のキーワード: tcr, mhc, mhc class i, immune system
• 由来する生物種: Mus musculus (mouse); 詳細
• 細胞内の位置: Membrane; Single-pass type I membrane protein: P01901; Secreted: P01887
• タンパク質・核酸の鎖数: 5
• 化学式量合計: 93630.09

構造登録者

Dai, S.,Huseby, E.,Scott-Browne, J.,Rubtsova, K.,Pinilla, C.,Crawford, F.,Marrack, P.,Yin, L.,Kappler, J.W. (登録日: 2011-04-09, 公開日: 2011-07-20, 最終更新日: 2023-09-13)

• 主引用文献: Yin, L.,Huseby, E.,Scott-Browne, J.,Rubtsova, K.,Pinilla, C.,Crawford, F.,Marrack, P.,Dai, S.,Kappler, J.W.; A Single T Cell Receptor Bound to Major Histocompatibility Complex Class I and Class II Glycoproteins Reveals Switchable TCR Conformers.; Immunity, 35:23-33, 2011; PubMed: 21683626; DOI: 10.1016/j.immuni.2011.04.017

実験手法

X-RAY DIFFRACTION (2.9 Å)