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3RFM

Thermostabilised adenosine A2A receptor in complex with caffeine

Summary for 3RFM
Entry DOI10.2210/pdb3rfm/pdb
Related3PWH 3REY
DescriptorAdenosine receptor A2a, CAFFEINE (2 entities in total)
Functional Keywordsinverse agonist, 7tm, gpcr, signaling protein, g-protein, membrane protein
Biological sourceHomo sapiens (human)
Cellular locationCell membrane; Multi-pass membrane protein: P29274
Total number of polymer chains1
Total formula weight36673.29
Authors
Dore, A.S.,Robertson, N.,Errey, J.C.,Ng, I.,Hollenstein, K.,Tehan, B.,Hurrell, E.,Bennett, K.,Congreve, M.,Magnani, F.,Tate, C.G.,Weir, M.,Marshall, F.H. (deposition date: 2011-04-06, release date: 2011-09-07, Last modification date: 2023-11-01)
Primary citationDore, A.S.,Robertson, N.,Errey, J.C.,Ng, I.,Hollenstein, K.,Tehan, B.,Hurrell, E.,Bennett, K.,Congreve, M.,Magnani, F.,Tate, C.G.,Weir, M.,Marshall, F.H.
Structure of the adenosine A(2A) receptor in complex with ZM241385 and the xanthines XAC and caffeine
Structure, 19:1283-1293, 2011
Cited by
PubMed: 21885291
DOI: 10.1016/j.str.2011.06.014
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3.598 Å)
Structure validation

217705

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