3REB
HIV-1 Nef protein in complex with engineered Hck-SH3 domain
Summary for 3REB
Entry DOI | 10.2210/pdb3reb/pdb |
Related | 3RBB 3REA |
Descriptor | Protein Nef, Tyrosine-protein kinase HCK (2 entities in total) |
Functional Keywords | hiv-1 nef, sh3 domain binding, signaling, hck sh3 domain, protein binding |
Biological source | HIV-1 M:B_ARV2/SF2 (HIV-1) More |
Total number of polymer chains | 4 |
Total formula weight | 58842.09 |
Authors | Schulte, A.,Blankenfeldt, W.,Geyer, M. (deposition date: 2011-04-04, release date: 2011-06-01, Last modification date: 2023-09-13) |
Primary citation | Breuer, S.,Schievink, S.I.,Schulte, A.,Blankenfeldt, W.,Fackler, O.T.,Geyer, M. Molecular design, functional characterization and structural basis of a protein inhibitor against the HIV-1 pathogenicity factor Nef. PLoS ONE, 6:e20033-e20033, 2011 Cited by PubMed: 21625496DOI: 10.1371/journal.pone.0020033 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.45 Å) |
Structure validation
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