3RE2
Crystal structure of menin reveals the binding site for Mixed Lineage Leukemia (MLL) protein
Summary for 3RE2
Entry DOI | 10.2210/pdb3re2/pdb |
Descriptor | Predicted protein, GLYCEROL (3 entities in total) |
Functional Keywords | menin, multiple endocrine neoplasia 1, tumor suppressor, mixed lineage leukemia, unknown function |
Biological source | Nematostella vectensis (Starlet sea anemone) |
Total number of polymer chains | 1 |
Total formula weight | 53090.08 |
Authors | Murai, M.J.,Chruszcz, M.,Reddy, G.,Grembecka, J.,Cierpicki, T. (deposition date: 2011-04-02, release date: 2011-07-13, Last modification date: 2024-02-21) |
Primary citation | Murai, M.J.,Chruszcz, M.,Reddy, G.,Grembecka, J.,Cierpicki, T. Crystal Structure of Menin Reveals Binding Site for Mixed Lineage Leukemia (MLL) Protein. J.Biol.Chem., 286:31742-31748, 2011 Cited by PubMed: 21757704DOI: 10.1074/jbc.M111.258186 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
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