3RCW
Crystal Structure of the bromodomain of human BRD1
Summary for 3RCW
Entry DOI | 10.2210/pdb3rcw/pdb |
Descriptor | Bromodomain-containing protein 1, 1-methylpyrrolidin-2-one, ACETATE ION, ... (5 entities in total) |
Functional Keywords | transcription, bromodomain, structural genomics, structural genomics consortium, sgc |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus : O95696 |
Total number of polymer chains | 8 |
Total formula weight | 125644.91 |
Authors | Filippakopoulos, P.,Keates, T.,Picaud, S.,Felletar, I.,Pike, A.C.W.,Krojer, T.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Weigelt, J.,Bountra, C.,Knapp, S.,Structural Genomics Consortium (SGC) (deposition date: 2011-03-31, release date: 2011-06-01, Last modification date: 2023-09-13) |
Primary citation | Filippakopoulos, P.,Picaud, S.,Mangos, M.,Keates, T.,Lambert, J.P.,Barsyte-Lovejoy, D.,Felletar, I.,Volkmer, R.,Muller, S.,Pawson, T.,Gingras, A.C.,Arrowsmith, C.H.,Knapp, S. Histone recognition and large-scale structural analysis of the human bromodomain family. Cell(Cambridge,Mass.), 149:214-231, 2012 Cited by PubMed: 22464331DOI: 10.1016/j.cell.2012.02.013 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.21 Å) |
Structure validation
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