3RC4
Molecular mechanisms of viral and host-cell substrate recognition by HCV NS3/4A protease
Summary for 3RC4
Entry DOI | 10.2210/pdb3rc4/pdb |
Related | 3RC5 3RC6 |
Descriptor | NS3/4A Protease, Product TRIF, SULFATE ION, ... (5 entities in total) |
Functional Keywords | drug resistance, drug design, protease inhibitors, serine protease, hydrolase, chymotrypsin-like, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Hepatitis C virus subtype 1a More |
Total number of polymer chains | 2 |
Total formula weight | 22919.25 |
Authors | Romano, K.P.,Schiffer, C.A. (deposition date: 2011-03-30, release date: 2011-05-04, Last modification date: 2023-09-13) |
Primary citation | Romano, K.P.,Laine, J.M.,Deveau, L.M.,Cao, H.,Massi, F.,Schiffer, C.A. Molecular mechanisms of viral and host cell substrate recognition by hepatitis C virus NS3/4A protease. J.Virol., 85:6106-6116, 2011 Cited by PubMed: 21507982DOI: 10.1128/JVI.00377-11 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.5 Å) |
Structure validation
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