3RBU

N-terminally AviTEV-tagged Human Glutamate Carboxypeptidase II in complex with 2-PMPA

3RBU の概要

• エントリーDOI: 10.2210/pdb3rbu/pdb
• 分子名称: Glutamate carboxypeptidase 2, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (10 entities in total)
• 機能のキーワード: peptidase, biotinylation, extracellular, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Cell membrane; Single-pass type II membrane protein. Isoform PSMA': Cytoplasm: Q04609
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 86480.67

構造登録者

Tykvart, J.,Sacha, P.,Barinka, C.,Starkova, J.,Knedlik, T.,Lubkowski, J.,Konvalinka, J. (登録日: 2011-03-30, 公開日: 2012-01-04, 最終更新日: 2023-09-13)

• 主引用文献: Tykvart, J.,Sacha, P.,Barinka, C.,Knedlik, T.,Starkova, J.,Lubkowski, J.,Konvalinka, J.; Efficient and versatile one-step affinity purification of in vivo biotinylated proteins: Expression, characterization and structure analysis of recombinant human glutamate carboxypeptidase II.; Protein Expr.Purif., 82:106-115, 2012; PubMed: 22178733; DOI: 10.1016/j.pep.2011.11.016

実験手法

X-RAY DIFFRACTION (1.6 Å)