3RBL
Crystal structure of Human aromatic L-amino acid decarboxylase (AADC) in the apo form
Summary for 3RBL
| Entry DOI | 10.2210/pdb3rbl/pdb |
| Related | 3RBF 3RCH |
| Descriptor | aromatic L-amino acid decarboxylase, CHLORIDE ION (2 entities in total) |
| Functional Keywords | apo enzyme, apo form, open conformation, open dimer, exposed, conformational change, parkinson, aadc deficiency, ddc, decarboxylase, plp, l-dopa, lyase |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 2 |
| Total formula weight | 107961.84 |
| Authors | Giardina, G.,Montioli, R.,Gianni, S.,Cellini, B.,Paiardini, A.,Borri Voltattorni, C.,Cutruzzola, F. (deposition date: 2011-03-29, release date: 2011-10-19, Last modification date: 2023-09-13) |
| Primary citation | Giardina, G.,Montioli, R.,Gianni, S.,Cellini, B.,Paiardini, A.,Voltattorni, C.B.,Cutruzzola, F. Open conformation of human DOPA decarboxylase reveals the mechanism of PLP addition to Group II decarboxylases. Proc.Natl.Acad.Sci.USA, 108:20514-20519, 2011 Cited by PubMed: 22143761DOI: 10.1073/pnas.1111456108 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (3.24 Å) |
Structure validation
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